KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGFR
All Species:
10
Human Site:
S356
Identified Species:
24.44
UniProt:
P43088
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43088
NP_000950.1
359
40055
S356
E
S
P
V
A
E
K
S
A
S
T
_
_
_
_
Chimpanzee
Pan troglodytes
XP_513513
359
40064
S356
E
S
P
V
A
E
K
S
A
S
T
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001104323
359
40044
S356
E
S
P
V
A
E
K
S
A
S
T
_
_
_
_
Dog
Lupus familis
XP_542174
343
37199
Cat
Felis silvestris
Mouse
Mus musculus
P43117
366
40681
E356
E
S
P
A
A
E
K
E
S
Q
Q
A
S
S
E
Rat
Rattus norvegicus
P43118
366
40636
E356
E
S
P
A
A
E
K
E
N
Q
Q
A
S
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512014
366
41408
I356
E
S
P
H
I
D
K
I
N
Q
Q
P
P
S
L
Chicken
Gallus gallus
NP_001038122
364
40949
Q353
E
S
P
V
S
S
K
Q
I
N
L
Q
P
L
S
Frog
Xenopus laevis
NP_001108252
367
41963
L363
G
T
E
R
K
C
E
L
S
E
T
K
_
_
_
Zebra Danio
Brachydanio rerio
XP_700529
390
43934
T358
V
I
S
R
P
D
F
T
P
L
D
G
T
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.3
31.7
N.A.
87.6
85.5
N.A.
84.6
80.4
68.3
47.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.8
49
N.A.
93.7
92.9
N.A.
90.7
88.1
81.1
62.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
40
40
N.A.
26.6
33.3
8.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
46.6
40
N.A.
33.3
46.6
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
50
0
0
0
30
0
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
20
0
0
0
0
10
0
0
0
0
% D
% Glu:
70
0
10
0
0
50
10
20
0
10
0
0
0
0
20
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
10
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
70
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
10
10
0
0
10
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
20
10
0
0
0
0
0
% N
% Pro:
0
0
70
0
10
0
0
0
10
0
0
10
20
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
30
30
10
0
0
0
% Q
% Arg:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
70
10
0
10
10
0
30
20
30
0
0
20
30
10
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
40
0
10
0
0
% T
% Val:
10
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
30
40
40
40
% _